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The milk thistle extract is usually prescribed to treat mushroom poisoning, alcoholic cirrhosis, chronic hepatitis, drug and alcohol-induced liver damage, acute viral hepatitis as well as fatty liver and many doctors consider it the most important supplement when it comes to maintaining a healthy liver. Silymarin is considered an antioxidant and an anti-inflammatory. Milk Thistle Table 5: Clinical Studies on Liver Disease & Liver Health; Study Information Outcome; Randomized, placebo-controlled, double-blind 2-year prospective clinical trial (). This may help ease symptoms … Silymarin is said to keep toxins from attaching to liver cells. * The liver performs many crucial functions including … Visit the Jarrow Formulas Store. The milk thistle liver detoxifying diet uses the milk thistle to help detoxify all of the chemicals and toxic garbage that accumulates in the body. If the leaves are ripped or crushed, a milky white liquid oozes out. For guidance from NCCIH on using PubMed, see How To Find Information About Complementary Health Approaches on PubMed. This may help ease symptoms from liver diseases like jaundice, cirrhosis, liver cancer, and fatty liver disease. tty (for deaf and hard-of-hearing callers): Email: info@nccih.nih.gov (link sends e-mail). We encourage you to discuss any decisions about treatment or care with your health care provider. Hangovers: Because milk thistle is known to aid the recovery of the liver from alcohol, many people take milk thistle before and after drinking to reduce the severity of the subsequent hangover. Prickly yet pretty, milk thistle is a plant with a long, thin stem, spiny leaves, and a purplish-pink thistle at the top. If you are experiencing … Tajmohammadi A, Razavi BM, Hosseinzadeh H. This plant is named for the white lines that streak across its green leaves. One of the liver’s most important functions is defending against toxins found in our environment. Researchers theorize that the active ingredient in milk thistle, silymarin, helps the liver … There’s conflicting research on the benefits of milk thistle for liver health. Milk Thistle. So far, no herbal supplement has been proved to be effective against hepatitis C. While more research is needed in that area, silymarin does have a good track record when it comes to treating a certain kind of mushroom poisoning. Milk thistle is thought to exert its protective effects on the liver through the promotion of liver cell growth and the prevention of oxidation and inflammation in the liver. Milk thistle for the fatty liver can be consumed in a variety of ways. We know little about whether milk thistle is effective in people, as only a few well-designed clinical studies have been conducted. Leptin Hormone & Supplements: Do They Work for Obesity & Weight Loss. Researchers found no changes in virus levels or quality of life in people who took the milk thistle, compared with those who took a placebo. Studies show that silymarin may help ease inflammation and promote cell repair. Milk thistle is one of the most powerful supplements available today that helps detox the liver, protect the body from free radical damage, and reduce inflammation. Jarrow Formulas Milk Thistle (Silymarin Marianum), Promotes Liver Health, 150 mg per Capsule, 200 Count. NCCIH has provided this material for your information. Milk thistle may produce allergic reactions, which tend to be more common among people who are allergic to plants in the same family (for example, ragweed, chrysanthemum, marigold, and daisy). Medical research on milk thistle and liver health has led to mixed results. Background Milk thistle is native to Europe and was introduced into North America by early colonists. What Is Complementary, Alternative, or Integrative Health? These unstable molecules are byproducts of your body’s functions. People mainly use the supplement to treat liver conditions. People who have diabetes should talk to their doctor before they take milk thistle because it may lower blood sugar. Little is known about whether it’s safe to use milk thistle during pregnancy or while breastfeeding. Liver related conditions indicating the use of milk thistle are varied, including, but not limited to: Alcoholic cirrhosis Chronic active hepatitis Drug and alcohol induced liver damage Acute viral hepatitis Fatty … U.S. Department of Health & Human Services, 9000 Rockville Pike Bethesda, Maryland 20892, U.S. Department of Health and Human Services. Silymarin is a flavonoid believed to have antioxidant properties.Milk thistle is sold as an oral capsule, tablet, powder and liquid extract. People with diabetes should use caution. ODS seeks to strengthen knowledge and understanding of dietary supplements by evaluating scientific information, supporting research, sharing research results, and educating the public. A 2016 … Supports liver health. Add the liquid extract to water or tea. Milk thistle may lower blood sugar levels in people with type 2 diabetes. Other uses not proven with research have included treating malaria , mushroom poisoning , spleen or gallbladder problems, menstrual problems, liver … It also holds free radicals in check. Medical research on milk thistle and liver health has led to mixed results. You might also hear it called Mary thistle or holy thistle. 4.6 out of 5 stars 5,905 ratings. Always talk to your doctor before you take any herbal supplements. Milk thistle is native to Europe’s Mediterranean region. Amanita phalloides is better known as the death cap for good reason. Talk to your doctor before you take milk thistle. Some people have reported nausea, gas, diarrhea, or loss of appetite. Milk Thistle for Liver Health. You can make the powder into a tea, blend it into a smoothie, or stir it into water. Milk thistle is promoted as a dietary supplement for hepatitis, cirrhosis, jaundice, diabetes, indigestion, and other conditions. Swallow the capsule or pill with a glass of water. Milk thistle may have been combined with other plants or extracts in a specific preparation to treat these conditions. Generally, it’s safe to take milk thistle in recommended doses. It can mimic estrogen. A service of the National Library of Medicine, PubMed® contains publication information and (in most cases) brief summaries of articles from scientific and medical journals. Milk thistle and compounds derived from it are commonly used as herbal supplements for liver problems, but study results are mixed. Website: https://pubmed.ncbi.nlm.nih.gov/. Over the years the liver gets bogged down by heavy metals, fatty foods, alcohol and chemicals, and becomes sluggish. Milk thistle provides many benefits to your overall health, but specifically supports liver function and liver health. It Can Boost Breast Milk Production. Milk thistle is a plant named for the white veins on its large prickly leaves.One of the active ingredients in milk thistle is silymarin, which is extracted from the plant's seeds. In the United States, it’s one of the most commonly used herbal supplements for liver issues. Laboratory studies suggest that milk thistle or some of its compounds have protective effects on the liver… One of the most common uses of milk thistle is to treat liver problems. It now grows all over the world, including northern Africa, South Australia, and parts of North and South America. Its resources include publications (such as Dietary Supplements: What You Need to Know), fact sheets on a variety of specific supplement ingredients and products (such as vitamin D and multivitamin/mineral supplements), and the PubMed Dietary Supplement Subset. Often considered a weed, it has been used for hundreds of years as a natural, herbal way to treat liver and gallbladder diseases. Historically, people have used milk thistle for liver … WebMD does not provide medical advice, diagnosis or treatment. 140 mg silymarin 3 times a day or placebo ↑ Survival rate in patients with cirrhosis of the liver… Historically, people have used milk thistle for liver disorders and gallbladder problems. The herbal extract of milk thistle is called silymarin, and the main component … Effect of silymarin on biochemical indicators in patients with liver disease: systematic review with meta-analysis. Morbidity and Mortality Weekly Report: “Amanita phalloides Mushroom Poisonings -- Northern California, December 2016.”. All rights reserved. It is not intended to substitute for the medical expertise and advice of your health care provider(s). For example, a comprehensive study in 2016 found that milk thistle can improve diet-induced liver damage. Studies show that silymarin may help ease inflammation and promote cell repair. Human and animal studies have shown that silymarin, an active compound in milk thistle, can prevent and normalize alcohol-induced damage in the liver … Other people have reported a headache or itchiness after they take it. There have been numerous studies suggesting milk thistle can support different aspects of liver health. 170 adult and child patients with cirrhosis of the liver (both alcoholic and non-alcoholic causes) (). But they can harm healthy cells and lead to health issues. Occasionally, people report various digestive side effects. Milk thistle is considered safe in dosages of 420 mg/day orally in divided doses for up to 41 months.Milić 2013, Tamayo 2007 One source suggests daily doses of 12 to 15 g of dry fruits for dyspepsia and disorders of the biliary system, while an extract containing 200 to 400 mg/day of silymarin is considered effective in various liver disorders.van Wyk 2004A dose of 140 mg of silymarin 3 times daily has been suggested for hepatic cirrhosis.Stolf 2017S. de Avelar CR, Pereira EM, de Farias Costa PR, et al. Myths and facts about this essential organ. Milk thistle is one of the most well-researched plants for the treatment of liver disease, including alcoholic liver disease, nonalcoholic fatty liver disease, and viral hepatitis. A major study found that people with hepatitis C didn’t benefit even from higher-than-normal doses of silymarin. News Release, University of California Santa Cruz. It’s not known whether milk thistle is helpful for other conditions. A small number of studies have suggested that milk thistle extract might be beneficial for diabetes, but the conclusions about its effectiveness are not definite. Get it back in working order so it can function at optimal levels by detoxing your liver with a milk thistle … [Database subscription]. Milk thistle can cause an allergic reaction, especially if you’re allergic to other plants in the same family. Best Milk Thistle … These include ragweed, daisies, marigolds, and chrysanthemums. Silybum marianum or milk thistle (MT) is the most well-researched plant in the treatment of liver disease. How Much Milk Thistle to Take to Repair Liver? The active complex of MT is a lipophilic extract from the seeds of the plant and is composed of three … These toxins lurk in the food we eat, prescription drugs, and even the clothing we wear! Don’t take it if you have breast, uterine, or ovarian cancer; endometriosis; or uterine fibroids. Accessed at naturalmedicines.therapeuticresearch.com on April 1, 2020. Together, you can make shared, well-informed decisions. Despite little clinical evidence to support the use of milk thistle … Basically, it depends on one’s condition. Duplication is encouraged. The terms “milk thistle” and “silymarin” are often used interchangeably. However, other studies don’t show any effect against another liver disease: hepatitis C, which is a viral infection. Milk thistle has been used as a natural remedy to treat liver problems, including fatty liver disease, for centuries. Although preliminary laboratory studies found that silymarin exerted antiviral, anti-inflammatory, antioxidant, and liver-protective effects, researchers still don’t fully understand why, and those benefits were not seen in clinical trials (studies in people) of milk thistle for liver … The COVID-19 outbreak is a rapidly evolving situation. Results from clinical trials of milk thistle for liver diseases have been conflicting or haven’t been clinically meaningful. Although milk thistle is most often used for liver conditions, such as hepatitis and cirrhosis, the herb is believed some to prevent or treat high cholesterol, diabetes, heartburn, upset stomach … It may affect how some medications work, including. Milk thistle is native to Europe and was introduced into North America by early colonists. Milk thistle is a natural herb with antioxidant and anti-inflammatory properties. Take charge of your health—talk with your health care providers about any complementary health approaches you use. An individual with normal health can take 140-800mg of milk thistle per day to treat fatty liver naturally. Usually the supplements contain 80%of milk thistle and some high quality products contain 95% of the original herb. © 2005 - 2019 WebMD LLC. The terms “milk thistle” and “silymarin” are often used interchangeably. It may have protective effects on the liver, preventing damage. A milk thistle liver detox is an important step in maintaining a properly functioning liver. Milk thistle() is available in different forms in the market – capsule, powder, and also in liquid form.If you purchase a powder form of milk thistle… | 129 answered questions. Milk thistle is found throughout the eastern United States, California, South America, Africa, Australia, and Asia. The terms milk thistle and silymarin are often used interchangeably, even though they aren’t exactly the same thing. Small Business Research Grant Program (SBIR), About Research Training and Career Development, Training Grant Application, Review, and Award Process, Integrative Medicine Research Lecture Series, Division of Extramural Research Sponsored by NCCIH, Division of Intramural Research Conducted at NCCIH, Know the Science: How Medications and Supplements Can Interact, Know the Science: 9 Questions To Help You Make Sense of Health Research, How To Find Information About Complementary Health Approaches on PubMed, Dietary Supplements: What You Need to Know. This publication is not copyrighted and is in the public domain. University of Rochester Medical Center: “Milk Thistle.”, National Center for Complementary and Integrative Health: “Hepatitis C and Dietary Supplements,” “Milk Thistle.”, Lancet Oncology: “Milk thistle: early seeds of potential.”, Huntington’s Outreach Project For Education, at Stanford: “About Free Radical Damage.”, Journal of Natural Products: “Silymarin Suppresses Cellular Inflammation By Inducing Reparative Stress Signaling.”, Journal of the American Medical Association: “Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial.”, Centers for Disease Control and Prevention Although some studies have shown positive results on milk thistle for people with chronic hepatitis C virus (HCV) infection, the overall research does not show a benefit. In clinical trials, milk thistle appears to be well tolerated in recommended doses. This supplement is … But silymarin has been helpful, and at least one clinical trial is underway. Also known by its … CDC health information   NIH research information, Common Names: milk thistle, Mary thistle, holy thistle, Latin Names: Silybum marianum, synonym Carduus marianus. The liver … Milk Thistle Liver Detox Milk Thistle Liver Detox is specially formulated to support overall liver health, essential to the body's overall health. It’s sometimes called silymarin, which is one of the main components of the plant’s seeds. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter. The mention of any product, service, or therapy is not an endorsement by NCCIH. It’s commonly used to detoxify the body and promote liver and gallbladder health. If you’re pregnant or breastfeeding, talk to your doctor before you take milk thistle or any herbal supplement. The Truth Behind the Top 10 Dietary Supplements, Natural Dietary Supplements: Facts Vs. Fad. Supplements & Your Liver - Does Milk Thistle Help Your Liver? herb native to southern Europe that typically grows over 10 feet tall and has red and purple flowers The Clearinghouse does not provide medical advice, treatment recommendations, or referrals to practitioners. … But is it really good for you, and can it really help your liver? Eating it can lead to liver damage and even liver failure. One reported effect of milk thistle is that it can boost breast … Image:ShutterStock. It’s responsible for most of the deaths from eating foraged mushrooms worldwide each year. Natural Medicines website. The milk thistle gets rid of this toxic sludge very effectively, and … The NCCIH Clearinghouse provides information on NCCIH and complementary and integrative health approaches, including publications and searches of Federal databases of scientific and medical literature. Milk thistle comes in powder, capsule, pill, or liquid extract forms. Some of the studies have been of poor quality, too. Is This an Emergency? Here's everything you need to know about it. 80 % of milk thistle for liver deaths from eating foraged mushrooms worldwide each year used as herbal supplements liver... Eastern United States, it ’ s responsible for most of the herb. Especially if you ’ re pregnant or breastfeeding, talk to your doctor before they take thistle! Thistle help your liver little about whether it’s safe to take milk thistle may blood! May affect How some medications work, including northern Africa, Australia, and liver. 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